Home  >  Products  >  BACE1 (Beta-secretase 1,Aspartyl Protease 2, ASP2, Asp 2, Beta-site Amyloid Precursor Protein Cleaving Enzyme 1, Beta-site APP Cleaving Enzyme 1, Memapsin-2, Membrane-associated Aspartic Protease 2, BACE, KIAA1149)
BACE1 (Beta-secretase 1,Aspartyl Protease 2, ASP2, Asp 2, Beta-site Amyloid Precursor Protein Cleaving Enzyme 1, Beta-site APP Cleaving Enzyme 1, Memapsin-2, Membrane-associated Aspartic Protease 2, BACE, KIAA1149)

BACE1 (Beta-secretase 1,Aspartyl Protease 2, ASP2, Asp 2, Beta-site Amyloid Precursor Protein Cleaving Enzyme 1, Beta-site APP Cleaving Enzyme 1, Memapsin-2, Membrane-associated Aspartic Protease 2, BACE, KIAA1149)

Cat no: B0002-91U

Supplier: United States Biological
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Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:50-1:100 Western Blot: 1:100-1:500 Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: B0002-91U
Reactivities: Human
Hosts: Rabbit
Applications: ELISA, Immunohistochemistry, Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, 0.9% sodium azide.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human BACE1.

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