Home  >  Products  >  Bad, ID (Bcl2 Antagonist of Cell Death, Bcl-2-binding Component 6, Bcl-2-like Protein 8, Bcl2-L-8, Bcl-XL/Bcl-2-associated Death Promoter, BBC6, BCL2L8)
Bad, ID (Bcl2 Antagonist of Cell Death, Bcl-2-binding Component 6, Bcl-2-like Protein 8, Bcl2-L-8, Bcl-XL/Bcl-2-associated Death Promoter, BBC6, BCL2L8)

Bad, ID (Bcl2 Antagonist of Cell Death, Bcl-2-binding Component 6, Bcl-2-like Protein 8, Bcl2-L-8, Bcl-XL/Bcl-2-associated Death Promoter, BBC6, BCL2L8)

Cat no: B0003-59N

Supplier: United States Biological
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The BCL2 antagonist of cell death protein (BAD) was previously known as proapoptotic BH3-only protein. The zebrafish genome was found to encode structural and functional homologs of the mammalian BCL-2 family members. These proteins are known to control the intrinsic apoptosis pathway. Upregulation of apoptotic genes, including BAD, was associated with an increase in apoptosis in zebrafish. Due to the functional and structural similarities between mammalian and zebrafish BCL homologs, zebrafish are a relevant model for the study of the intrinsic apoptotic pathway. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:5000-1:20,000 Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher. Control Peptide: B0003-59S Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: B0003-59N
Reactivities: Zebrafish/Fish
Hosts: Rabbit
Applications: ELISA, Western Blot
Size: 250ul
Form: Supplied as a liquid in 40mM MOPS, pH 7.5, 0.1% BSA, 0.05% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Kratz, E et al (2006) Cell Death Differ. 13(10):1631-1640. 2. Amali, AA et al (2006) J. Biomed. Sci. 13(2):225-232.
Additional info: Recognizes zebrafish Bad.

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