Home  >  Products  >  BAFF Receptor (BAFFR, BAFF-R, BAFF Receptor, B Cell-Activating Factor Receptor, BLyS Receptor 3, BR3, CD268, CD268 antigen, MGC138235, Tumor Necrosis Factor Receptor Superfamily Member 13C, TNFRSF13C)
BAFF Receptor (BAFFR, BAFF-R, BAFF Receptor, B Cell-Activating Factor Receptor, BLyS Receptor 3, BR3, CD268, CD268 antigen, MGC138235, Tumor Necrosis Factor Receptor Superfamily Member 13C, TNFRSF13C)

BAFF Receptor (BAFFR, BAFF-R, BAFF Receptor, B Cell-Activating Factor Receptor, BLyS Receptor 3, BR3, CD268, CD268 antigen, MGC138235, Tumor Necrosis Factor Receptor Superfamily Member 13C, TNFRSF13C)

Cat no: B0003-68B

Supplier: United States Biological
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Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF, BLyS, TALL-1, THANK, and zTNF4. BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. Two receptors, TACI and BCMA, for BAFF were originally identified. A third receptor was identified recently and designated BAFF-R and BR3 for BLyS receptor 3. Unlike BCMA and TACI, which bind to BAFF and April, BAFF- R/BR3 is specific for BAFF and plays a predominant role in BAFF induced B cell development and survival. BAFF and its receptors are involved in B cell associated autoimmune diseases, and activate NF-kB and c-Jun N-terminal kinase. Applications: Suitable for use in Western Blot. Other applications have not been tested. Recommended Dilutions: Western Blot: 0.5-4 ug/ml Optimal dilutions to be determined by the researcher. Control Peptide: B0003-68B1 Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: B0003-68B
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinitiy chromatography.
Additional info: Recognizes mouse BAFF-R. Species crossreactivity: human and rat.

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