Home  >  Products  >  BAG1 (BAG Family Molecular Chaperone Regulator 1, BAG-1, BCL-2 Associated Athanogene 1, BCL-2-associated Athanogene 1, BCL2-associated Athanogene, RAP46)

BAG1 (BAG Family Molecular Chaperone Regulator 1, BAG-1, BCL-2 Associated Athanogene 1, BCL-2-associated Athanogene 1, BCL2-associated Athanogene, RAP46)

Cat no: B0003-84G


Supplier: United States Biological
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Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1-2ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: B0003-84G
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: BCL-2 Binding Athanogene 1, Glucocorticoid Receptor-associated Protein RAP46
References: 1. Gotz, R. et al. (2005) Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells. Nat. Neurosci. 8: 1169-1178. 2. Liman, J. et al. (2005) Interaction of BAG1 and Hsp70 mediates neuroprotectivity and increases chaperone activity. Mol. Cell Biol. 25: 3715-3725. 3. Krajewska, M. et al. (2006) Expression of BAG-1 protein correlates with aggressive behavior of prostate cancers. Prostate. 66: 801-810. 4. Clemo, N.K. et al. (2005) The role of the retinoblastoma protein (Rb) in the nuclear localization of BAG-1: implications for colorectal tumour cell survival. Biochem. Soc. Trans. 33: 676-678.
Additional info: Recognizes human BAG1 (N-TERMINAL). Species Crossreactivity: mouse.

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