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BARD1 (R8) Peptide

BARD1 (R8) Peptide

Cat no: BS2408P

Supplier: Bioworld Technology, Inc.
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The BRCA1 gene is expressed in numerous tissues, including breast and ovary, and encodes a predicted protein of 1863 amino acids. This protein contains a RING domain near the N-terminus and appears to encode a tumor suppressor. BARD1 (BRCA1-associated RING domain protein 1) and BAP1 (BRCA1-associated protein 1) have both been shown to bind to the N-terminus of BRCA1 and are potential mediators of tumor suppression. BARD1 contains an N-terminal RING domain and three tandem ankyrin repeats. The C-terminus of BARD1 contains a region with sequence homology to BRCA1, termed the BRCT domain. BAP1 is an ubiquitin hydrolase and has been shown to enhance BRCA1-mediated cell growth suppression.
Catalogue number: BS2408P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q99728
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide BARD1 (R8). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: BRCA1-associated RING domain protein 1; BARD-1; BARD 1
Additional info: This peptide can be used with studies using BS2408 BARD1 (R8) pAb.

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