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Barrier-to-Autointegration Factor 1 (BANF1, BCRP1, Breakpoint Cluster Region Protein 1, D14S1460)

Barrier-to-Autointegration Factor 1 (BANF1, BCRP1, Breakpoint Cluster Region Protein 1, D14S1460)

Cat no: B0094-28B

Supplier: United States Biological
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The protein encoded by this gene was identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The endogenous function of the protein is unknown. The protein forms a homodimer which localizes to the nucleus and is specifically associated with chromosomes during mitosis. This protein binds to DNA in a non-specific manner and studies in rodents suggest that it also binds to lamina-associated polypeptide 2, a component of the nuclear lamina. Applications: Suitable for Western Blot and Immunohistochemistry. Recommended Dilutions: Immunohistochemistry (paraffin): 2.5ug/ml. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: B0094-28B
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, 0.02% sodium azide.
P type: Pab
Purity: Purified by Immunoaffinity chromatography.
Additional info: Recognizes human Breakpoint Cluster Region Protein, Uterine Leiomyoma, 1; Barrier To Autointegration Factor (BCRP1) (BANF1). Species Crossreactivity: mouse and rat.

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