BATF, also known as SFA2, is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. BATF is strongly expressed in mature T and B lymphocytes, and is up-regulated after transformation by human T-cell leukemia virus type I. BATF functions as a tissue-specific modulator of the AP-1 transcription complex in human cells. BATF also associates with IFP35, a leucine zipper protein that translocates to the nucleus following IFN treatment.
Source:
Recombinant corresponding to human BATF, fused to His-tag at N-terminus, expressed in E. coli.
Molecular Weight:
~16.2kD
Sequences of Amino Acids:
MGSSHHHHHH SSGLVPRGSH MPHSSDSSDS SFSRSPPPGK QDSSDDVRRV QRREKNRIAA QKSRQRQTQK ADTLHLESED LEKQNAALRK EIKQLTEELK YFTSVLNSHE PLCSVLAAST PSPPEVVYSA HAFHQPHVSS PRFQP
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.