Home  >  Products  >  Bax (BCL2-associated X protein, Apoptosis regulator BAX, cytoplasmic isoform beta, Apoptosis regulator BAX, membrane isoform alpha, BAX protein, cytoplasmic isoform delta, BAX protein, cytoplasmic isoform gamma, BCL2L4)
Bax (BCL2-associated X protein, Apoptosis regulator BAX, cytoplasmic isoform beta, Apoptosis regulator BAX, membrane isoform alpha, BAX protein, cytoplasmic isoform delta, BAX protein, cytoplasmic isoform gamma, BCL2L4)

Bax (BCL2-associated X protein, Apoptosis regulator BAX, cytoplasmic isoform beta, Apoptosis regulator BAX, membrane isoform alpha, BAX protein, cytoplasmic isoform delta, BAX protein, cytoplasmic isoform gamma, BCL2L4)

Cat no: B0175-02J

Supplier: United States Biological
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Applications: Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry (paraffin-embedded sections). Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: B0175-02J
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 1ml
Form: PBS with 0.2% gelatin
P type: Pab
Isotype: IgG
Purity: Purified
Alternative names: Apoptosis regulator BAX, BCL2 associated X protein
References: Bae J et al. Underphosphorylated BAD interacts with diverse antiapoptotic Bcl-2 family proteins to regulate apoptosis. Apoptosis 6:319-30 (2001). Fridman JS et al. Cytochrome c depletion upon expression of Bcl-XS. J Biol Chem 276:4205-10 (2001). Coldwell MJ et al. The p36 isoform of BAG-1 is translated by internal ribosome entry following heat shock. Oncogene 20:4095-100 (2001). Wei MC et al. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 292:727-30 (2001). Lindenboim L et al. Bcl-xS and Bax induce different apoptotic pathways in PC12 cells. Oncogene 19:1783-93 (2000). Huang Z Bcl-2 family proteins as targets for anticancer drug design. Oncogene 19:6627-31 (2000). Eversole-Cire P et al. Synergistic effect of Bcl-2 and BAG-1 on the prevention of photoreceptor cell death. Invest Ophthalmol Vis Sci 41:1953-61 (2000). Reed JC Double identity for proteins of the Bcl-2 family. Nature 387:773-6 (1997). Yang E et al. Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death. Cell 80:285-91 (1995).
Additional info: Reacts specifically with Bax. Species Crossreactivity: Crossreacts with Human, Rat and Mouse.

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