Home  >  Products  >  BCA-1 Human, Recombinant (B Cell Attracting Chemokine1, B Lymphocyte Chemoattractant, BLC, CXCL13, BLR1 Ligand)

BCA-1 Human, Recombinant (B Cell Attracting Chemokine1, B Lymphocyte Chemoattractant, BLC, CXCL13, BLR1 Ligand)

Cat no: B0395


Supplier: United States Biological
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BCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach. It exerts its activities through its only receptor CXCR5. BCA-1/BLC is a potent chemoattractant for B lymphocytes and induces weak chemotactic response in T cells and macrophages. It manifests no activity on neutrophils and monocytes. Recombinant Human BCA-1 is a 10.3kD protein containing 85 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines. AA Sequence: VLEVYYTSLR CRCVQESSVF IPRRFIDRIQ ILPRGNGCPR KEIIVWKKNK SIVCVDPQAE WIQRMMEVLR KRSSSTLPVP VFKRKIP Biological Activity: Determined by its ability to chemoattract human B cells using a concentration range of 1-10ng/ml. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with Acetic acid. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: B0395
Size: 5ug
Form: Supplied as a lyophilized powder with no additives. Reconstitute with Acetic acid to a concentration of 0.1-1.0mg/ml. Do not vortex. Further dilute with PBS, 0.1% BSA or HSA.
Purity: (same/more than) 98% by SDS-PAGE and HPLC. Endotoxin: (same/less than) 0.1ng/ug (1EU/ug)

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