Bcl-2 Antibody

Cat no: 251711

Supplier: ABBIOTEC

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Description
Additional Information

Apoptosis regulator Bcl-2 (Bcl-2) suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Bcl-2 regulates cell death by controlling mitochondrial membrane permeability. Bcl-2 functions in a feedback loop system with caspases, inhibiting caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). A chromosomal aberration involving Bcl-2 has been found in chronic lymphatic leukemia.

Catalogue number:	251711
Reactivities:	Human
Size:	0.1 mg
Accession:	P10415
Antigen:	Thyroglobulin-conjugated synthetic peptide encompassing a sequence within the N-term region of human Blcl-2.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Additional info:	Apoptosis regulator Bcl-2; BCL2