BCL2-like protein 2, also known as BCL2L2, is a member of the Bcl-2 family of proteins that regulates outer mitochondrial membrane permeability. BCL2L2 is an anti apoptotic member that prevents release of cytochrome c from the mitochondria intermembrane space into the cytosol. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. It is required for normal sperm maturation.
Recombinant human BCL2L2, fused to His-tag at N-terminus expressed in E.coli.
Applications:
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution:
Optimal dilutions to be determined by the researcher.
Molecular Weight: 20.9kD (192aa)
Endotoxin: (same/less than)1EU/1ug (LAL)
Amino acid Sequence:
MGSSHHHHHH SSGLVPRGSH MATPASAPDT RALVADFVGY KLRQKGYVCG AGPGEGPAAD PLHQAMRAAG DEFETRFRRT FSDLAAQLHV TPGSAQQRFT QVSDELFQGG PNWGRLVAFF VFGAALCAES VNKEMEPLVG QVQEWMVAYL ETRLADWIHS SGGWAEFTAL YGDGALEEAR
RLREGNWASV RT
Molecular Weight: 20.9kD (192aa)
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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