Home  >  Products  >  BD2 (beta Defensin-2, beta 2 Defensin, Defensin beta 2, BD 2, BD-2, DEFB2, DEFB-2, HBD 2, HBD2, HBD-2, DEFB102, Skin Antimicrobial Peptide 1, SAP1) (Biotin)
BD2 (beta Defensin-2, beta 2 Defensin, Defensin beta 2, BD 2, BD-2, DEFB2, DEFB-2, HBD 2, HBD2, HBD-2, DEFB102, Skin Antimicrobial Peptide 1, SAP1) (Biotin)

BD2 (beta Defensin-2, beta 2 Defensin, Defensin beta 2, BD 2, BD-2, DEFB2, DEFB-2, HBD 2, HBD2, HBD-2, DEFB102, Skin Antimicrobial Peptide 1, SAP1) (Biotin)

Cat no: B0901-03B1

Supplier: United States Biological
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Expression of BD-2 is induced during inflammation in response to bacterial products and cytokines, and is initially expressed in a precursor form, which is cleaved to release the C-terminal active portion of the protein. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilutions: ELISA: 1ug/ml Western Blot: 0.1-0.2ug/ml Optimal dilutions to be determined by the researcher. Recommended Pair: Suitable for use as the detection or conjugate (label) antibody in sandwich immunoassay. Matched to B0901-03B as the capture or solid phase antibody. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile PBS, 0.1% BSA. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: B0901-03B1
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Conjugates: Biotin
Size: 50ug
Form: Supplied as a lyophilized powder from PBS. No preservative added. Labeled with Biotin. Reconstitute with 500ul of sterile PBS, 0.1% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by affinity chromatography.
Alternative names: Beta 4 Defensin, Defensin 4 beta, Defensin beta 4, DEFB4, DEFB-4
References: 1. Bals, R. et al. (1998) Human beta-Defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung. J. Clin. Invest. 102: 874-880. 2. Harder, J. et al. (2000) Mucoid Pseudomonas aeruginosa, TNF-a, and IL-1beta, but not IL-6, induce human beta-Defensin-2 in respiratory epithelia. Am. J. Respir. Cell Mol. Biol. 22: 714-721. 3. Harder, J. et al. (2000) Mucoid Pseudomonas aeruginosa, TNF-a, and IL-1beta, but not IL-6, induce human beta-Defensin-2 in respiratory epithelia. Am. J. Respir. Cell Mol. Biol. 22: 714-721.
Additional info: Recognizes human Defensin beta-2, a 4.3kD cationic antimicrobial peptide expressed primarily by epithelial cells of the respiratory tract and skin, and an important component of the innate immune response against microbial infections.

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