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BD4 (beta Defensin-4) (Biotin)

BD4 (beta Defensin-4) (Biotin)

Cat no: B0903-25B

Supplier: United States Biological
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Defensin beta 4 (BD4), a secreted cationic antimicrobial peptide and member of the beta-defensin family, highly expressed in the testis, which plays an important role in innate immunity. Studies have shown that the expression of BD-4 is up-regulated in respiratory epithelial cells, following infection by both gram-positive and gram-negative bacteria, and that BD-4 acts in synergy with lysozyme and BD-3. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 0.25-1ug/ml Western Blot: 0.1- 0.2ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: B0903-25B
Reactivities: Human
Hosts: Rabbit
Applications: ELISA, Western Blot
Conjugates: Biotin
Size: 50ug
Form: Supplied as a lyophilized powder in PBS, pH7.2. Labeled with Biotin. Reconstitute with 500ul sterile PBS, 0.1% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Conejo-Garcia, J.R.et al. (2001) Human beta-defensin 4: a novel inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity FASEB. J. 15:1819-1821.
Additional info: Recognizes human defensin beta 4 (BD4).

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