Benzoylecgonine-Linker (Cocaine)

Cat no: B1077-14B

Supplier: United States Biological

0 reviews | Write a Review Pencil

Read More on Supplier Website

Description
Additional Information

Cocaine is a potent psychoactive substance, also known as 'coke' and 'snow' and it is extracted from the leaves of the South American shrub Erythroxylon coca (5, 6). Cocaine hydrochloride is a fine powder that may be insufflated (snorted), producing quick absorption and onset of effects. Intravenous use leads to a quick and powerful but brief effect. 'Crack' is a freebase form of cocaine which when smoked produces an immediate 'high', with a more intense euphoria and so has become the choice for many users (2, 5, 7). Cocaine causes severe psychological dependence. In the body, cocaine is rapidly converted to metabolites by enzymatic and chemical processes. The two major urinary metabolites of cocaine are benzoylecgonine (BZG) and ecgonine methyl ester (8). The plasma half-life of cocaine is only 0.7-1.5 hours and its urinary excretion is rapid. There is very little of the parent cocaine molecule excreted in urine (~1-9%). Benzoylecgonine is the primary urinary metabolite, accounting for 30-40% of the dose eliminated in the urine (2, 6, 9). Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 2ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	B1077-14B
Hosts:	Sheep
Applications:	ELISA
Size:	100ul
Form:	Supplied as a liquid in 20mM phosphate, 150mM sodium chloride, pH 7.2, 0.09% sodium azide.
P type:	Pab
Isotype:	IgG
Purity:	Purified
References:	1. Beselt RC., Urine Drug Screening by Immunoassay: Interpretation of Results. In: Beselt RC, Advances in Analytical Toxicology, vol 1, chapter 5, 81-123. 2. Eskridge KD. and Guthrie SK., Clinical issues associated with urine testing of substances of abuse. Pharmacotherapy, 1997, 17(3): 497-510. 3. Wu AHB., Onigbinde TA., Johnson KG. and Wimbish GH. Alcohol-specific cocaine metabolites in serum and urine of hospitalized patients, J.Anal.Toxicol. 1992, 16: 132-137. 4. Zhang JY. and Folz RL. Cocaine metabolism: identification of four previously unreported cocaine metabolites in human urine, J.Anal.Toxicol. 1990, 14 (4): 201-205.
Additional info:	Recognizes Benzoylecgonine-Linker.

See Full Product Listings >

Benzoylecgonine-Linker (Cocaine)

Cat no: B1077-14B

Get Quote

About Biosave

Product Categories

Information


Get a Quote Direct from United States Biological




By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*