Beta-Amyloid [31-35] Antibody

Cat no: 251354

Supplier: ABBIOTEC

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Description
Additional Information

Beta-amyloid production results from cleavage in the e, Xenopus/Amphibian,tracellular domain of APP by the beta-secretase (BACE1) , which results in the production of the APP C-terminal fragment C99. This fragment is further cleaved by the gamma-secretase at residues 40-42 to produce beta-amyloid 40 and 42 peptides. Beta-amyloid aggregation and neuritic plaque formation are pathologic hallmarks of Alzheimer disease.

Catalogue number:	251354
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P05067
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within human b-amyloid 31-35.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Beta-Amyloid [31-35]; APP; ABPP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; Protease ne, Xenopus/Amphibian,in-II; PN-II; APPI; PreA8; Beta-amyloid protein 40; Beta-APP40