Beta-Amyloid Protein Antibody

Cat no: 252052

Supplier: ABBIOTEC

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Description
Additional Information

Amyloid beta A4 protein (beta-amyloid protein) functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and a, Xenopus/Amphibian,onogenesis. Beta-amyloid protein is involved in cell mobility and transcription regulation through protein-protein interactions. Beta-amyloid protein promotes transcriptional activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Defects in APP are the cause of Alzheimer disease type 1 (AD1). AD1 is a familial early-onset form of Alzheimer disease. Alzheimer disease is a neurodegenerative disorder characterized by progressive dementia, loss of cognitive abilities, and deposition of fibrillar amyloid proteins as intraneuronal neurofibrillary tangles, e, Xenopus/Amphibian,tracellular amyloid plaques and vascular amyloid deposits.

Catalogue number:	252052
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P05067
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within human beta-amyloid protein.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	APP; ABPP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; Protease ne, Xenopus/Amphibian,in-II; PN-II; APPI; PreA4