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BEX1 (Brain Expressed X-linked Protein 1)

BEX1 (Brain Expressed X-linked Protein 1)

Cat no: B1081-75

Supplier: United States Biological
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Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three proteins must be present for toxicity to occur. It begins with the binding of PA to its cell-surface receptor, ATR (Anthrax Toxin Receptor), at which point PA is cleaved and the resulting 63kD carboxyl-terminal fragment binds to LF and EF. LF is a protease that is known to cleave members of the mitogen-activated protein kinase kinase (MAPKK) family(2). Positive Control: Jurkat whole cell lysate Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: B1081-75
Reactivities: Human, Mouse
Hosts: Mouse
Applications: Western Blot
Size: 100ug
Form: Ascities fluid with 0.05% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein G affinity chromatography.
Alternative names: BEX2, GR74
References: 1. Yang,Q.S., Xia,F., Gu,S.H., Yuan,H.L., Chen,J.Z., Yang,Q.S., Ying,K., Xie,Y. and Mao,Y.M. Cloning and expression pattern of a spermatogenesis-related gene, BEX1, mapped to chromosome Xq22. Biochem. Genet. 40 (1-2), 1-12 (2002).
Additional info: Species Crossreactivity: Cross reacts with Human. Predicted to cross react with Mouse.

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