BIGH3 Antibody

Cat no: 251911

Supplier: ABBIOTEC

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Description
Additional Information

Transforming growth factor-beta-induced protein ig-h3 (BIGH3) binds to type I, II, and IV collagens. BIGH3 plays a role in cell-collagen interactions. In cartilage, BIGH3 is involved in endochondral bone formation. Defects in BIGH3 are the cause of epithelial basement membrane corneal dystrophy (EBMD), also known as Cogan corneal dystrophy or map-dot-fingerprint type corneal dystrophy. EBMD is a bilateral anterior corneal dystrophy characterized by grayish epithelial fingerprint lines, geographic map-like lines, and dots (or microcysts) on slit-lamp e, Xenopus/Amphibian,amination. Pathologic studies show abnormal, redundant basement membrane and intraepithelial lacunae filled with cellular debris. Although this disorder usually is not considered to be inherited, families with autosomal dominant inheritance have been identified.

Catalogue number:	251911
Reactivities:	Human, Mouse
Applications:	Western Blot
Size:	0.1 mg
Accession:	Q15582
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human BIGH3.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Transforming growth factor-beta-induced protein ig-h3; Beta ig-h3; Kerato-epithelin; RGD-containing collagen-associated protein; RGD-CAP; TGFBI; BIGH3