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Bikaverin (NSC 215139, BRN 0358013, Lycopersin, Mycogonin, Passiflorin)

Cat no: 044599


Supplier: United States Biological
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Antibiotic. Antiprotozoal. Antifungal. Anticancer. ATP synthesis inhibitior. Haemolytic agent. Antioomycete. Spermidine-induced autoactivation inhibitor. Plasma hyaluronan-binding protein (PHBP) inhibitor (active form). Storage and Stability: Short-term Storage: +4 degrees C Long-term Storage: -20 degrees C Stable for at least 3 years after receipt when stored at -20 degrees C.
Catalogue number: 044599
Size: 250ug
Purity: >95% (HPLC)
Alternative names: NSC 215139, BRN 0358013, Lycopersin, Mycogonin, Passiflorin
References: Product Reference: ?Bikaverin, an antibiotic from ibberella fujikoi, effective against Leishmania brasiliensis: J. Balan, et al.; Folia Microbiol. 15, 479 (1970) ?Isolation and characterization of a fungal vacuolation factor (bikaverin): J.W. Cornforth, et al.; J. Chem. Soc. Perkin 16, 2786 (1971) ?New potential cytotoxic and antitumor substances I. In vitro effect of bikaverin and its derivatives on cells of certain tumors: J. Fuska, et al.; Neoplasma 22, 335 (1975) ?Effects of bikaverin on purine nucleotide synthesis and catabolism in Ehrlich ascites tumor cells in vitro: J.F. Henderson, et al.; Biochem. Pharmacol. 26, 1973 (1977) ?Inhibition of mitochondrial functions by the antibiotics, bikaverin and duclauxine: L. Kovac, et al.; J. Antibiot. (Tokyo) 31, 616 (1978) ?Effects of selected secondary metabolites of Fusarium moniliforme on unscheduled synthesis of DNA by rat primary hepatocytes: W.P. Norred, et al.; Food Chem. Toxicol. 30, 233 (1992) ?Search for cell motility and angiogenesis inhibitors with potential anticancer activity: beauvericin and other constituents of two endophytic strains of Fusarium oxysporum: J. Zhan, et al.; J. Nat. Prod. 70, 227 (2007) ?Bikaverin and fusaric acid from Fusarium oxysporum show antioomycete activity against Phytophthora infestans: S.W. Son, et al.; J. Appl. Microbiol. 104, 692 (2008) ?Purpurin as a specific inhibitor of spermidine-induced autoactivation of the protease plasma hyaluronan-binding protein: N. Nishimura, et al.; Biol. Pharm. Bull. 33, 1430 (2010) ?Bikaverin production and applications: M.C. Limon, et al.; Appl. Microbiol. Biotechnol. 87, 21 (2010) (Review) ?

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