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Biliverdin IX beta Reductase,1-206aa, Recombinant, Human (BLVRB)

Cat no: B1150-03


Supplier: United States Biological
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Biliverdin reductase B (BLVRB) is an enzyme (EC 1.3.1.24) that converts biliverdin to bilirubin, converting a double-bond between the second and third pyrrole ring into a single-bond. BLVRB is found that major erythrocytic heme catabolic pathway in humans and most mammalian species. Biliverdin reductase is abundantly expressed in kidney, spleen, liver and brain as well as at lower levels in the thymus and minimal levels being detected in testis. Sequence of amino acids: MAVKKIAIFG ATGQTGLTTL AQAVQAGYEV TVLVRDSSRL PSEGPRPAHV VVGDVLQAAD VDKTVAGQDA VIVLLGTRND LSPTTVMSEG ARNIVAAMKA HGVDKVVACT SAFLLWDPTK VPPRLQAVTD DHIRMHKVLR ESGLKYVAVM PPHIGDQPLT GAYTVTLDGR GPSRVISKHD LGHFMLRCLT TDEYDGHSTY PSHQYQ Molecular Weight: 22.1kD (206aa) Endotoxin: (same/less than)1.0 EU/ug of protein (determined by LAL method) Storage and Stability: For long-term storage, aliquot and store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: B1150-03
Size: 100ug
Form: Supplied as a liquid in 20mM Tris pH 8.5, 10% glycerol, 1mM DTT.
Purity: (same/more than) 95% by SDS PAGE. Recombinant human BLVRB protein was expressed in E. coli and purified by using conventional chromatography techniques.
References: 1. L. Lee Grismer., et al. (2007). Herpetologica. 63(3):392-400 2. Baranano DE., et al. (2002). Proc Natl Acad Sci USA. 10; 99(25):16093-8

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