Biotin anti-human beta2-microglobulin

Cat no: 316308

Supplier: BioLegend

0 reviews | Write a Review Pencil

Description
Additional Information

beta2-microglobulin (beta2M) is a 12 kD nonpolymorphic Ig like protein. It is a non-membrane-anchored glycoprotein and is noncovalently associated with 39-44 kD polymorphic heavy chains of MHC class I molecules to form HLA class I antigen complex. In association with HLA class I, beta2M is expressed on all leukocytes, platelets, endothelial cells, and epithelial cells. beta2M plays an essential role both in governing MHC class I molecules stability and in promoting antigen binding and presenting the antigen to CD3/TCR complex of CD8+ T cells.

Catalogue number:	316308
Reactivities:	Human
Hosts:	Mouse
Applications:	Flow Cytometry
Conjugates:	Biotin
Size:	100 microg
Clone:	2M2
Gene:	567
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.5 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Concentration:	0.5 mg/ml
Antigen:	Purified human beta2-microglobulin
Isotype:	Mouse IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	b2-M, b2M