Biotin anti-human IL-21

Cat no: 513102

Supplier: BioLegend

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Description
Additional Information

Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset and has pleiotropic effects on both innate and adaptive immune responses.These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells.Recent studies have shown that IL-21 is also an autocrine cytokine that potently induces T(H)17 differentiation and suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.

Catalogue number:	513102
Reactivities:	Human
Hosts:	Mouse
Applications:	Immunofluorescence
Conjugates:	Biotin
Size:	500 microg
Clone:	2B2-G20
Gene:	59067
Dilutions:	Each lot of this antibody is quality control tested by ELISA assay. For ELISA detection applications, a concentration range of 0.5-2.0 microg/ml is recommended. To obtain a linear standard curve, serial dilutions of IL-21 recombinant protein ranging from 2000 to 15 pg/ml are recommended for each ELISA plate.
Storage buffer:	The antibody solution should be stored undiluted at 4C. Do not freeze.
Concentration:	0.5 mg/ml
Antigen:	Recombinant full length human IL-21
Isotype:	Mouse IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Interleukin 21