Biotin anti-mouse CD107b (Mac-3)

Cat no: 108508

Supplier: BioLegend

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Description
Additional Information

Mac-3 is a 110 kD type I membrane glycoprotein, also known as CD107b and LAMP-2. It is expressed on lysosomal membranes and the plasma membrane of macrophages and some myeloid cell lines. In the bone marrow, few cells display Mac-3 antigen on the surface, but a large proportion express Mac-3 in the cytoplasm. CD107b has been identified as a ligand for galaptin, an S-type lectin present in the extracellular matrix. Mac-3/CD107b is upregulated in some tumors and increased expression has been correlated with enhanced metastatic potential.

Catalogue number:	108508
Reactivities:	Mouse
Hosts:	Rat
Applications:	Flow Cytometry, Immunohistochemistry
Conjugates:	Biotin
Size:	500 microg
Clone:	M3/84
Gene:	16784
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 0.25 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C. Do not freeze.
Concentration:	0.5 mg/ml
Antigen:	Membrane glycoproteins from C57BL/6 mouse peritoneal exudate cells
Isotype:	Rat IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	CD107b, LAMP-2, Mac3