Biotin anti-mouse CD1d (CD1.1, Ly-38)

Cat no: 123505

Supplier: BioLegend

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Description
Additional Information

CD1d, known as CD1.1 and Ly-38, is a 48 kD type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with beta2-microglobulin. In humans, CD1 family consists of group I proteins (CD1a, CD1b, and CD1c), group II (CD1d), and group III (CD1e). But CD1d is the only CD1 molecule has been found in mouse. Mouse CD1d has broad tissue distribution, and is found on leukocytes, dendritic cells, epithelial cells, and thymocytes. CD1d plays a role in non-peptide glycolipid antigen presentation to CD1d-restricted T cells. It has been shown that PKCdelta is a critical regulator of CD1d-mediated antigen presentation.

Catalogue number:	123505
Reactivities:	Mouse
Hosts:	Rat
Applications:	Flow Cytometry, Immunohistochemistry
Conjugates:	Biotin
Size:	50 microg
Clone:	1B1
Gene:	12479
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.25 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C. Do not freeze.
Concentration:	0.5 mg/ml
Antigen:	Mouse Cd1.1 cDNA-transfected RMA-S mouse T lymphoma
Isotype:	Rat IgG2b, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	CD1.1, Ly-38