Biotin anti-mouse CD262 (DR5, TRAIL-R2)

Cat no: 119904

Supplier: BioLegend

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Description
Additional Information

CD262 is a 55 kD protein also known as DR5, TRAIL-R2, Apo-2, TRICK2, and KILLER. DR5 is member 10B of the TNF receptor superfamily (TNFRSF10B), widely expressed in normal tissues and some tumor cell lines. The DR5 receptor binds to TRAIL and interacts with the cytoplasmic proteins TRADD and RIP. TRAIL binding to DR5 activates NF- kappaB and induces apoptosis. DR5 is induced by wild-type p53.

Catalogue number:	119904
Reactivities:	Mouse
Hosts:	Hamster
Applications:	Flow Cytometry
Conjugates:	Biotin
Size:	500 microg
Clone:	MD5-1
Gene:	21933
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C. Do not freeze.
Concentration:	0.5 mg/ml
Antigen:	Mouse DR5-Ig fusion protein
Isotype:	Armenian Hamster IgG
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	DR5, TRAIL-R2, TRICK2, KILLER, TNFRS10B