Biotin anti-rat CD53

Cat no: 204303

Supplier: BioLegend

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Description
Additional Information

CD53 is a 35-45 kD type III tetraspan membrane protein. It is expressed on all leukocytes and a subset of thymocytes, but not on platelets, erythrocytes, or non-hematopoietic cells. CD53 has been proposed to be involved in signal transduction and thymopoiesis. It has been shown to interact with a number of proteins, including IL-4, CD20, CD2, CD9, IL-2, VLA-4, and CD4. Cross-linking of CD53 promotes B cell activation. The CD53 antigen is highly glycosylated and treatment with endoglycosidase F reduces the apparent molecular weight of this protein by approximately 25kD.

Catalogue number:	204303
Reactivities:	Rat
Hosts:	Mouse
Applications:	Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation
Conjugates:	Biotin
Size:	100 microg
Clone:	OX-44
Gene:	12508
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C. Do not freeze.
Concentration:	0.5 mg/ml
Antigen:	Rat T cell blasts
Isotype:	Mouse IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	MOX44, OX-44, Tspan-25