Biotin anti-rat CD53

CD53 is a 35-45 kD type III tetraspan membrane protein. It is expressed on all leukocytes and a subset of thymocytes, but not on platelets, erythrocytes, or non-hematopoietic cells. CD53 has been proposed to be involved in signal transduction and thymopoiesis. It has been shown to interact with a number of proteins, including IL-4, CD20, CD2, CD9, IL-2, VLA-4, and CD4. Cross-linking of CD53 promotes B cell activation. The CD53 antigen is highly glycosylated and treatment with endoglycosidase F reduces the apparent molecular weight of this protein by approximately 25kD.

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SPECIFICATIONS

Catalog Number

204303

Size

100 microg

Applications

FC, IF, IHC, IP

Hosts

Mouse

Reactivities

Rat

Conjugates

Biotin

Clone

OX-44

Antigen

Rat T cell blasts

Gene Id

12508

Isotype

Mouse IgG1, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C. Do not freeze.

Alternative Names

MOX44, OX-44, Tspan-25

Regulatory Status

RUO