BLK (1E6) Antibody

Cat no: 253094

Supplier: ABBIOTEC

0 reviews | Write a Review Pencil

Description
Additional Information

BLK (B lymphoid tyrosine kinase) is a 505-amino acid protein (~56KDa), belongs to the Src non-receptor tyrosine kinases family. Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization and membrane trafficking. Blk is e, Xenopus/Amphibian,pressed e, Xenopus/Amphibian,clusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid e, Xenopus/Amphibian,pression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.

Catalogue number:	253094
Reactivities:	Human
Applications:	Immunofluorescence
Size:	0.1 ml
Accession:	P51451
Antigen:	Purified recombinant fragment of human BLK e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	1E6
Additional info:	Tyrosine-protein kinase Blk; B lymphocyte kinase; p55-Blk; BLK