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BMP-2 Polyclonal Antibody

Cat no: ABP57423

BMP-2 Polyclonal Antibody

BMP2 ?bone morphogenetic protein 2)encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of BMP2 causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.

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SPECIFICATIONS

Catalog Number

ABP57423

Size

30micro l, 100micro l, 200micro l

Applications

ELISA, IF, IHC-F, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Gene Id

650

Isotype

Rabbit IgG

Accession

P12643

Clonality

Polyclonal

Concentration

1 mg/ml

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