BMPR1A Antibody

Cat no: 200151

Supplier: ABBIOTEC

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Description
Additional Information

Upon ligand binding, BMPR1A forms a receptor comple, Xenopus/Amphibian, consisting of two type II and two type I transmembrane Ser/Thr kinases. The type I receptors are activated by the type II receptors by using a phosphorylation mechanism, and subsequently bind SMAD transcriptional regulators. Defects in BMPR1A are the cause of juvenile polyposis syndrome, Cowden disease and hereditary mi, Xenopus/Amphibian,ed polyposis syndrome 2, which lead to gastrointestinal, breast, thyroid, endometrial and colon cancers.

Catalogue number:	200151
Reactivities:	Human, Mouse, Rabbit, Xenopus/Amphibian
Applications:	Western Blot
Size:	0.1 mg
Accession:	P36894, NP_004320
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human BMPR1A.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Bone morphogenetic protein receptor type IA; Serine/threonine-protein kinase receptor R5; SKR5; Activin receptor-like kinase 3; ALK-3; CD292 antigen; BMPR1A; ACVRLK3