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Bone Morphogenetic Protein 10 (BMP10)

Bone Morphogenetic Protein 10 (BMP10)

Cat no: B2553-37J

Supplier: United States Biological
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Bone morphogenetic protein 10 (BMP-10) is a TGF-b superfamily member whose expression is restricted to the developing and postnatal heart. It is synthesized as a 424aa pre-proprotein with a putative 21aa signal peptide, a 292aa propeptide, and a 108aa mature protein. Mature BMP-10 is secreted as a 25kD disulfide-linked homodimer. The mouse BMP-10 proprotein shares 86-95aa sequence identity with human and rat BMP-10, respectively. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: 8-25ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: B2553-37J
Reactivities: Mouse
Hosts: Rat
Size: 100ug
Form: Supplied as a lyophilized powder in PBS, trehalose. Reconstitute with sterile PBS to 0.5mg/ml.
P type: Mab
Isotype: IgG2A
Purity: Purified by Protein A/G affinity chromatography.
Additional info: Recognizes mouse BMP-10. Species sequence homology: recombinant human BMP-10, rhBMP-8a (10%), recombinant mouse BMP-8b. Does not react with rmBMP-3, -4, -5, -6, -7, -9, -15, rhBMP-1.1, -2, -3b, propeptide rhBMP-10.

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