Bone Morphogenetic Protein 11 (GDF-11) is a secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. It plays critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern. It exists as a disulfide-linked homodimer. It belongs to the TGF-beta family.
Applications:
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended Dilution:
Immunohistochemistry: formalin-fixed paraffin-embedded
Optimal dilutions to be determined by the researcher.
Storage and Stability:
Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.