Home  >  Products  >  Brain Natriuretic Peptide (Brain Natriuretic Peptide 32, BNP 32, Gamma Brain Natriuretic Peptide, Natriuretic Peptide Brain Type, Natriuretic Peptide Precursor B, Natriuretic Peptides B, NPPB Protein)
Brain Natriuretic Peptide (Brain Natriuretic Peptide 32, BNP 32, Gamma Brain Natriuretic Peptide, Natriuretic Peptide Brain Type, Natriuretic Peptide Precursor B, Natriuretic Peptides B, NPPB Protein)

Brain Natriuretic Peptide (Brain Natriuretic Peptide 32, BNP 32, Gamma Brain Natriuretic Peptide, Natriuretic Peptide Brain Type, Natriuretic Peptide Precursor B, Natriuretic Peptides B, NPPB Protein)

Cat no: B2702-29U

Supplier: United States Biological
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Human brain natriuretic peptide (BNP) is a secreted protein which is a member of the natriuretic peptide family. BNP is a cardiac hormone, which is synthesised as a pro-hormone (proBNP), and is proteolytically cleaved to release a biologically active fragment (BNP), and an inactive fragment (NT-proBNP) into the circulation. BNP is predominantly secreted from the cardiac ventricles in response to volume and pressure overload, and results in a number of biological activities including natriuresis, diuresis, vasorelaxation, and inhibition of the sympathetic nervous system. A high concentration of BNP in the bloodstream is indicative of heart failure. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Hybridoma: Sp2/0 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: B2702-29U
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Western Blot
Size: 200ug
Form: Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein A affinity chromatography.
References: 1. Clerico, A. et al. (2006) Clinical relevance of biological variation: the lesson of brain natriuretic peptide (BNP) and NT-proBNP assay. Clin. Chem. Lab. Med. 44: 366-378, 2. Pfister, R. and Schneider, C.A. (2004) Natriuretic peptides BNP and NT-pro-BNP: established laboratory markers in clinical practice or just perspectives? Clin. Chim. Acta. 349: 25-38.
Additional info: Recognizes the human brain natriuretic peptide (BNP). Crossreacts with proBNP.

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