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Brain-Specific Angiogenesis Inhibitor 1 (BAI1, KIAA4089, R75078, B830018M07Rik, mKIAA4089)

Cat no: B2704-02K


Supplier: United States Biological
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Reduced expression of BAI1 is observed in some glioblastomas leading to neovascularisation, suggesting that BAI1 may be an excellent gene therapy candidate for the treatment of brain tumors. BAI1 is also thought to be transcriptionally regulated by p53. Applications: Suitable for use in Immunohistochemistry (paraffin). Other applications not tested. Recommended Dilution: Immunohistochemistry: 10-30ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: B2704-02K
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Immunohistochemistry
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.7, 0.09% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: BAI 1, BAI-1
References: 1. Kang, X. et al. (2006) Antiangiogenic activity of BAI1 in vivo: implications for gene therapy of human glioblastomas. Cancer Gene Ther. 13: 385-392.
Additional info: Recognizes human BAI1 (N-TERMINAL). Species Crossreactivity: mouse.

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