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BRCA1 Antibody

BRCA1 Antibody

Cat no: 251301

Supplier: ABBIOTEC
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Breast cancer type 1 susceptibility protein (BRCA1) is an E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. Defects in BRCA1 are a cause of susceptibility to breast cancer (BC).
Catalogue number: 251301
Reactivities: Human, Mouse, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: P38398
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human BRCA1.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: BRCA1; Breast cancer type 1 susceptibility protein; RING finger protein 53; RNF53
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