Home  >  Products  >  BRCA1 (Breast Cancer 1, Breast Cancer 1 Early Onset, Breast Cancer Type 1 Susceptibility Protein, BRCC1, Breast Ovarian Cancer Susceptibility, Papillary Serous Carcinoma of the Peritoneum, PSCP, RING Finger Protein 53, RNF53)
BRCA1 (Breast Cancer 1, Breast Cancer 1 Early Onset, Breast Cancer Type 1 Susceptibility Protein, BRCC1, Breast Ovarian Cancer Susceptibility, Papillary Serous Carcinoma of the Peritoneum, PSCP, RING Finger Protein 53, RNF53)

BRCA1 (Breast Cancer 1, Breast Cancer 1 Early Onset, Breast Cancer Type 1 Susceptibility Protein, BRCC1, Breast Ovarian Cancer Susceptibility, Papillary Serous Carcinoma of the Peritoneum, PSCP, RING Finger Protein 53, RNF53)

Cat no: B2709-06A

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
The interaction between BRCA1 and BARD1 (BRCA1 associated RING domain 1) through an amino-terminal RING finger domain, is implicated in RNA processing following DNA damage, and also in the mediation of tumor suppression by BRCA1. Gene mutations in BRCA1 are known to greatly enhance susceptibility to inherited breast, breast-ovarian and prostate cancers, and BRCA1 is therefore commonly used as a diagnostic marker for breast cancer. Applications: Suitable for use in Immunoprecipitation and Western Blot. Other applications not tested. Recommended Dilution: Immunoprecipitation: 1-4ug/mg Western Blot: 1:1,000-1:10,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: B2709-06A
Reactivities: Human
Hosts: Rabbit
Applications: Immunoprecipitation, Western Blot
Size: 50ug
Form: Supplied as a liquid in tris-citrate/phosphate, 0.09% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: BRAC1, IRIS
References: 1. Venkitaraman, A.R. (2001) Functions of BRCA1 and BRCA2 in the biological response to DNA damage. J. Cell Sci. 114: 3591-3598.
Additional info: Recognizes human BRCA1.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave