Brilliant Violet 421(TM) anti-mouse NK-1.1

Cat no: 108731

Supplier: BioLegend

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NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-gamma production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

Catalogue number:	108731
Reactivities:	Mouse
Hosts:	Mouse
Applications:	Flow Cytometry, Immunofluorescence
Size:	125 microl
Clone:	PK136
Gene:	17059
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?5 microl per million cells or 5 microl per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.Brilliant Violet 421(TM) excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50 nm is recommended for detection. Brilliant Violet 421(TM) is a trademark of Sirigen Group Ltd.
Storage buffer:	The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Antigen:	NK-1+ cells from mouse spleen and bone marrow
Isotype:	Mouse IgG2a, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	NKR-P1C, NKR-P1B, Ly-55, CD161b, CD161c, NK1.1

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Brilliant Violet 421(TM) anti-mouse NK-1.1

Cat no: 108731

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