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BST1 (ADP-ribosyl Cyclase 2, Bone Marrow Stromal Antigen 1, BST-1, Cyclic ADP-ribose Hydrolase 2, cADPr Hydrolase 2, CD157)

BST1 (ADP-ribosyl Cyclase 2, Bone Marrow Stromal Antigen 1, BST-1, Cyclic ADP-ribose Hydrolase 2, cADPr Hydrolase 2, CD157)

Cat no: B3000-02A

Supplier: United States Biological
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Bone marrow stromal cell antigen 1 (BST1) is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. BST1, which is also known as ADP-rybosyl cyclase 2, is an enzyme which is expressed by BST1 gene in human. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (formalin fixed paraffin embedded): 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: B3000-02A
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry
Size: 100ug
Form: Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Lee, B.O. et al. Arthritis. Rheum. 39:629
Additional info: Recognizes human BST1. Species Crossreactivity: chimpanzee. Species sequence homology: orangutan.

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