BTK Antibody

Cat no: 251688

Supplier: ABBIOTEC

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Description
Additional Information

Tyrosine-protein kinase BTK (BTK) is a tyrosine kinase that plays a crucial role in B-cell ontogeny. Defects in BTK are the cause of , Xenopus/Amphibian,-linked agammaglobulinemia (, Xenopus/Amphibian,LA) also known as , Xenopus/Amphibian,-linked agammaglobulinemia type 1 (AGM, Xenopus/Amphibian,1) or immunodeficiency type 1 (IMD1). , Xenopus/Amphibian,LA is a humoral immunodeficiency disease which results in developmental defects in the maturation pathway of B-cells. Affected boys have normal levels of pre-B-cells in their bone marrow but virtually no circulating mature B-lymphocytes. This results in a lack of immunoglobulins of all classes and leads to recurrent bacterial infections.

Catalogue number:	251688
Reactivities:	Human
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q06187
Antigen:	Recombinant human BTK.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG2b
Additional info:	BTK; Tyrosine-protein kinase BTK; Bruton tyrosine kinase; Agammaglobulinaemia tyrosine kinase; ATK; B-cell progenitor kinase; BPK; AGM, Xenopus/Amphibian,1; ATK; BPK