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BUB3 Polyclonal Antibody

Cat no: CAC07698

BUB3 Polyclonal Antibody

BUB3 Polyclonal Antibody

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SPECIFICATIONS

Price

323.00 USD

Catalog Number

CAC07698

Size

100 micro g

Applications

IHC, WB

Hosts

Rabbit

Conjugates

Unconj

Purity

Protein G purified, >95%

Target

BUB3

Clonality

Polyclonal

Storage Temp

Aliquot and store at -20 degrees C. Minimize freezing and thawing.

Research Area

For research use only. Not for diagnostic procedures.

Shipping Temp

Blue ice

Additional Info

Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1.

Alternative Names

Mitotic checkpoint protein BUB3,BUB3

SUPPLIER INFO

Biomatik Corporation

Applications

ELISA

Reactivities

Hum

More info

Applications

ELISA

Reactivities

Hum

More info

Applications

ELISA

Reactivities

Hum

More info

Applications

ELISA

Reactivities

Hum

More info

Applications

ELISA

Reactivities

Hum

More info

Applications

ELISA

Reactivities

Hum

More info

Applications

ELISA

Reactivities

Hum

More info

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