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C/EBP-(gamma) (E64) pAb

C/EBP-(gamma) (E64) pAb

Cat no: BS2558

Supplier: Bioworld Technology, Inc.
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The transcription factor C/EBP (alpha) (CCAAT-enhancer binding protein) is a heatstable, sequence-specific DNA-binding protein first purified from rat liver nuclei that binds avidly to several different cis-regulatory DNA sequences commonly associated with viral and cellular genes transcribed by RNA polymerase II. C/EBP (alpha) regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP (alpha) uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic alpha helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C/EBP (alpha) appears to function exclusively in terminally differentiated, growth-arrested cells. Additional family members include C/EBP (beta), C/EBP (gamma),C/EBP (delta) and C/EBP E, all of which exhibit similar DNA-binding specificities and affinities to C/EBP (alpha). Furthermore, C/EBP (beta) and C/EBP (delta) readily form heterodimers both with each other as well as with C/EBP (alpha).
Catalogue number: BS2558
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunofluorescence, Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P53567
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 50-100 of Human C/EBP-(gamma).
Species: C/EBP-(gamma) (E64) detects endogenous levels of C/EBP-(gamma) protein.
Molecular weight: ~ 22 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: CCAAT/enhancer-binding protein gamma; C/EBP gamma; CEBPG; C/EBP(gamma); CEBP(gamma)
Additional info: For research use only, not for use in diagnostic procedure.

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