c-erbB2, p185 (HER2, neu Receptor)

Cat no: C0015-01K

Supplier: United States Biological

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c-erbB-2 is a membrane-associated oncoprotein having considerable sequence homology to EGFR. C-erbB-2 is the second member of the EGF receptor tyrosine kinase family of growth factor receptors. Overexpression of c-erbB-2/HER-2 is reportedly a marker of poor prognosis in node-positive and in defined subsets of node-negative breast cancer. Elevated levels of c-erbB-2/HER-2 has also been implicated in response to chemotherapy. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Paraffin sections): 10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Catalogue number:	C0015-01K
Reactivities:	Human
Hosts:	Rabbit
Applications:	Immunohistochemistry
Size:	50ug
Form:	Supplied as a liquid in PBS, 0.1% sodium azide.
P type:	Pab
Purity:	Purified by immunoaffinity chromatography.
Alternative names:	EC=2.7.10.1, ERBB2, NGL, P185ERBB2, TKR1
Additional info:	Recognizes Human ERBB-2 Receptor Protein Tyrosine Kinase (ERBB2). Species Crossreactivity: Human.

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c-erbB2, p185 (HER2, neu Receptor)

Cat no: C0015-01K

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