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c-Fos (Fos)

c-Fos (Fos)

Cat no: C0030-04

Supplier: United States Biological
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c-Fos is a nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. It has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. c-Fos expression increases upon a variety of stimuli, including growth factors, cytokines, neurotransmitters, polypeptide hormones, stress and cell injury. Belongs to the bZIP family. Fos subfamily. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Subcellular Localization: Nucleus. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C0030-04
Reactivities: Rat, Rabbit
Hosts: Sheep
Applications: ELISA
Size: 500ug
Form: Supplied as a lyophilized powder. Reconstitute in 500 ul of sterile water. Centrifuge to remove any insoluble material.
P type: Pab
Isotype: IgG
Purity: Purified by affinity chromatography.
Alternative names: Cellular oncogene fos, FBJ murine osteosarcoma viral v fos oncogene homolog, FBJ Osteosarcoma Virus, FOS protein, G0 G1 switch regulatory protein 7, G0S7, Oncogene FOS, Proto oncogene protein c fos, v fos FBJ murine osteosarcoma viral oncogene homolog
References: 1. Vanstraaten et al (1983) Proc. Natl. Acad. Sci. 80: 3183 ; 2. Minson J. et al. (1994) Brain Res. 646: 44-52
Additional info: Recognizes c-fos. Species Crossreactivity: rat, rabbit, and hamster. Peptide Sequence Homology: human, mouse, rat, hamster and cat

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