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c-jun

Cat no: C5815-01L


Supplier: United States Biological
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Cellular Localization: Nuclear Positive Control: NIH/3T3 Applications: Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry (Fr). Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C5815-01L
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 1ml
Form: Supplied as a liquid in PBS, pH 7.2.
P type: Pab
Isotype: IgG
Purity: Purified
Alternative names: AP1, Activator Protein 1, Enhancer Binding Protein AP1, JUN, JUN protein, JUNC, Jun Activation Domain Binding Protein, Jun oncogene, Proto oncogene cJun, Transcription Factor AP1, V jun avian sarcoma virus 17 oncogene homolog, p39, vJun Avian Sarcoma Virus 17 Oncogene Homolog
References: Shaulian E & Karin M AP-1 in cell proliferation and survival. Oncogene 20:2390-400 (2001). Fu S et al. Heparin-binding epidermal growth factor-like growth factor, a v-Jun target gene, induces oncogenic transformation. Proc Natl Acad Sci U S A 96:5716-21 (1999). Liebermann DA et al. AP-1 (Fos/Jun) transcription factors in hematopoietic differentiation and apoptosis. Int J Oncol 12:685-700 (1998). Karin M et al. AP-1 function and regulation. Curr Opin Cell Biol 9:240-6 (1997). Curran T Fos and Jun: oncogenic transcription factors. Tohoku J Exp Med 168:169-74 (1992). Bos TJ et al. The carboxy terminus of the viral Jun oncoprotein is required for complex formation with the cellular Fos protein. Oncogene 4:123-6 (1989). Rauscher FJ et al. Fos and Jun bind cooperatively to the AP-1 site: reconstitution in vitro. Genes Dev 2:1687-99 (1988).
Additional info: Reacts with c-Jun p39 Species Crossreactivity: Crossreacts with Human, Rat and Mouse.

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