Home  >  Products  >  C-Jun (Transcription Factor AP-1, Activator Protein 1, AP1, Proto-oncogene c-Jun, V-jun Avian Sarcoma Virus 17 Oncogene Homolog, p39, JUN)
C-Jun (Transcription Factor AP-1, Activator Protein 1, AP1, Proto-oncogene c-Jun, V-jun Avian Sarcoma Virus 17 Oncogene Homolog, p39, JUN)

C-Jun (Transcription Factor AP-1, Activator Protein 1, AP1, Proto-oncogene c-Jun, V-jun Avian Sarcoma Virus 17 Oncogene Homolog, p39, JUN)

Cat no: C5815-01Q

Supplier: United States Biological
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c-Jun is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins, and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. The MAP kinase homologue, JNK, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. The activity of JNK is stimulated by the same signals that activate c-Jun. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C5815-01Q
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 30% glycerol, 0.5 BSA 5mM EDTA, 0.01% thimerosl.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human c-Jun.

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