c-Myc

Cat no: C0035-30A

Supplier: United States Biological

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c-Myc is a transcription factor with apparent molecular weight of 62-67 kD which plays an important role in the control of cell growth, cell cycle progression, neoplasia, and apoptotic cell death. It contains a basic helix-loop-helix leucine zipper domain required for dimerization and binds DNA as an heterodimer with MAX protein. c-Myc is overexpressed in different tumors such as colorectal, gastric, gallbladder, hepatic, mammary, pulmonary, prostatic, endocrine, as well as hematopoietic neoplasms. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1000 Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Catalogue number:	C0035-30A
Reactivities:	Human
Hosts:	Rabbit
Applications:	ELISA, Western Blot
Size:	1mg
Form:	Supplied as a liquid in PBS, pH 7.2.
P type:	Pab
Purity:	Purified by Protein G affinity chromatography.
References:	Eisenman, R.N. (2001) Genes & Dev. 15,2023-2030. Plengaris, S. & Khan, M. (2003) Arch. Biochem. Biophys. 416,129-136.Knoepfler, P.S. (2007) Cancer Res. 67,5061-6063.
Additional info:	Recognizes human c-Myc

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c-Myc

Cat no: C0035-30A

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