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C-Peptide (Hyperproinsulinemia, Insulin Precursor, IRDN, Proinsulin)

C-Peptide (Hyperproinsulinemia, Insulin Precursor, IRDN, Proinsulin)

Cat no: C7905-01P

Supplier: United States Biological
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C-peptide also known as connecting peptide is a peptide released when proinsulin is cleaved to produce insulin. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry: Frozen sections Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C7905-01P
Reactivities: Human
Hosts: Mouse
Applications: Immunohistochemistry
Size: 250ug
Form: Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by ammonium sulfate precipitation.
References: 1. Hilgert, I. et al. (1991) A monoclonal antibody applicable for determination of C-peptide of human proinsulin by RIA.Hybridoma. 10: 379-86. 2. Afrikanova, I. et al. (2011) Inhibitors of Src and Focal Adhesion Kinase Promote Endocrine Specification: Impact on the Derivation of Beta Cells from Human Pluripotent Stem Cells.J Biol Chem. Aug 18. [Epub ahead of print]3. Vasic, D. and Walcher, D. (2012) C-Peptide: A New Mediator of Atherosclerosis in DiabetesMediators of Inflammation. Article ID: 858692.
Additional info: Recognizes human C-peptide. It can also be used to detect proinsulin.

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