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C-Peptide (Hyperproinsulinemia, Insulin Precursor, Proinsulin)

Cat no: C7905-01G


Supplier: United States Biological
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C Peptide is part of the molecule of Proinsulin, that consists of three parts: C Peptide and two long strands of amino acids (called the alpha and beta chains) that later become linked together to form the insulin molecule. From every molecule of proinsulin, one molecule of insulin plus one molecule of C Peptide are produced. C peptide is released into the blood stream in equal amounts to insulin. A test of C peptide levels will show how much insulin the body is making. Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Cellular Localization: Secreted Applications: Suitable for use in RID and ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C7905-01G
Reactivities: Human
Hosts: Mouse
Applications: ELISA
Size: 100ug
Form: PBS with pH 7.4
P type: Mab
Isotype: IgG1,k
Purity: As reported
Alternative names: Hyperproinsulinemia, Insulin Precursor, Proinsulin
Additional info: Binds to the human free C-peptide and proinsulin molecules. No cross reactivity with human, bovine, porcine insulins.Affinity (Kd) > 1 x 10e8. Species Crossreactivity: Crossreacts with Human. Not yet tested in other species.

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