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C-Reactive Protein (CRP, C-Reactive Protein Pentraxin Related, MGC88244, PTX 1, PTX1)

C-Reactive Protein (CRP, C-Reactive Protein Pentraxin Related, MGC88244, PTX 1, PTX1)

Cat no: C7907-04L2

Supplier: United States Biological
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C-reactive protein (CRP) is a calcium-binding plasma protein which is significantly up-regulated during the acute phase response. CRP has been shown to bind phosphocholine residues, apoptotic cells and constituents of micro-organisms, and can lead to activation of leukocytes and the complement system, and the clearance of apoptotic cells. CRP is produced in the liver in response to interleukin-1 (IL-1) and IL-6 secretion, and has a monomer molar mass of 25kDa, and native cyclic pentamer mass of 125kDa. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: frozen sections Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C7907-04L2
Reactivities: Human
Hosts: Sheep
Applications: ELISA, Immunohistochemistry
Size: 1ml
Form: Supplied as a liquid in PBS, pH 7.4. Preservative free.
P type: Pab
Isotype: IgG
Purity: Purified by Protein G affinity chromatography.
References: 1. de Ferranti, S.D. and Rifai, N. (2007) C-reactive protein: a nontraditional serum marker of cardiovascular risk. Cardiovasc. Pathol. 16: 14-21. 2. de Ferranti, S.D. and Rifai, N. (2007) C-reactive protein: a nontraditional serum marker of cardiovascular risk. Cardiovasc. Pathol. 16: 14-21 3. Yeh, E.T. (2004) CRP as a mediator of disease. Circulation. 109(21 Suppl 1):II11-4. 4. Yeh, E.T. (2004) CRP as a mediator of disease. Circulation. 109(21 Suppl 1):II11-4.
Additional info: Recognizes human C-Reactive Protein.

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