c-Src Antibody

Cat no: 251505

Supplier: ABBIOTEC

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Description
Additional Information

Proto-oncogene tyrosine-protein kinase Src (c-Src) is a non-receptor protein tyrosine kinase that plays pivotal roles in numerous cellular processes such as proliferation,Mouse,igration, and transformation. In concert with PTK2Bovine, c-Src plays an important role in osteoclastic bone resorption. Both the formation of a SRC-PTK2B comple, Xenopus/Amphibian,, and c-SRC kinase activity are necessary for this function. Once it is recruited to the activated integrins by PTK2Bovine, c-Src phosphorylates CBL which in turn induces the activation and recruitment of phosphatidylinositol 3-kinase to the cell membrane in a signaling pathway that is critical for osteoclast function. C-Src promotes energy production in osteoclasts by activating mitochondrial cytochrome C o, Xenopus/Amphibian,idase.

Catalogue number:	251505
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P12931
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human c-SRC.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	SRC; Proto-oncogene tyrosine-protein kinase Src; pp60c-src; p60-Src; c-Src; SRC1