C4 Complement Antibody

Cat no: 250123

Supplier: ABBIOTEC

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Description
Additional Information

The complement component C4 plays a central role in the activation of the classical pathway of the complement system. C4 is cleaved by activated C1 which removes the C4a anaphylato, Xenopus/Amphibian,in from the alpha chain. The remaining active C4b fragment becomes a subunit of the C3 convertase (C4b2a) and the C5 convertase (C3bC4b2a) enzymes of the classical complement pathway. The C4a anaphylato, Xenopus/Amphibian,in is a mediator of local inflammatory process. The C4A6 allotype is totally deficient in hemolytic activity. This antibody recognizes the human complement C4 in ELISA.

Catalogue number:	250123
Reactivities:	Human
Size:	0.1 mg
Accession:	P0C0L4,Porcine0C0L5
Antigen:	Purified human complement C4 protein
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	mouse IgG1
Clonality:	KT29
Additional info:	Complement C4-A; Acidic complement C4; C4 beta chain; C4-A alpha chain; C4a anaphylato, Xenopus/Amphibian,in; C4b-A; C4d-A; C4 gamma chain; C4A; C4B; Basic complement C4; C4-B alpha chain; C4b-B; C4d-B